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M. REZA-UL (RAJ) KARIM,

Professor and Specialist Microbiologist
B.Sc. (Hons) 1962, University of Karachi, Microbiology
M.S., 1966, University of Minnesota, Veterinary Microbiology
Ph.D., 1974, Univeristy of Montana, Missoula, Microbiology

rkarim@d.umn.edu
153B SSB, 726-7250

I am a teacher at heart and committed to helping students learn and achieve. As a microbiologist, I believe that knowledge is not only taught, but also sought. The exciting moments are when students discover points of contact between their personal lives and the materials we are studying in microbiology, immunology , virology and Food Preservation, Sanitation, and Bioterrorism. During the teaching, learning, and advising activities, I listen, talk, and attempt to stir the noblest part of everyone and get the students to think what they are, what they do, how they do it and what difference does it make, if we do it or not. Also I help them to contemplate ideals when most people don't have time for. Furthermore, I fashion an environment in which a student really understands “marvel of flight” through research using plant originated substances against emerging and reemerging infectious diseases in particular certain virus, bacteria and fungi.

Knowledge is our strength. I do believe in the globalization of knowledge through collaborative education and scholarly activities. Our campus is a “small global village” in terms of learning, intellectual and cultural activities where a diverse body of students, faculty/scholars and staff can develop a passion for knowledge and research reaching their maximum potential. I am committed to being more caring, more friendly, more inviting and more open to fulfill our mission in quality undergraduate education and advising. Students are the reasons for my employment, and not an interruption. I find myself learning from them every day and they are my challenge.

Research:

MICROBIOLOGY/VIROLOGY/IMMUNOLOGY using Plant Originated Chemicals and Other Immunogens

Recent Publications:

  • Amjad, Muhammad, Robert M. Carlson, Pavel Krasutsky, and M. Reza-ul Karim, 2004. Inhibition of Epstein-Barr Virus by the Triterpenoid Betulin diphosphate and uvaol. J. Microbiology and Biotechnology, 14 (5).

  • Gong, Yunhao, M. Raj Karim, Carolyn A. Luscombe, Izabelle Gadawski, Teresa Tam, Jianhua Chu, David Gibson, Robert Carlson and Stephen L. Sacks. 2004.  The Synergistic Effects of Betulin with Acyclovir against Herpes Simplex Viruses.  Antiviral Research 64: 127-130.

  • Hu, L.D., Caple, R., Kamperdick, C., Diep, N.T. and Karim, M.R. 2004.  Isomeranzin against Herpes simplex virus invitro from Clausena heptaphyla (ROXB) W. ARN:  Isolation, Structure and Biological Assay. Journal of Chemistry, Vol. 42 (1), p 115-120.

  • Amjad, Muhammad, Carlson, Robert, Krasutsky, Pavel and Karim, M.R. 2003. Antiviral Activities of Triterpenoid Betulin Derivatives Against Herpes Simplex Viruses. Pakistan Journal of Microbiology, Vol. 5, Page 1-7.
  • M. Amjad, R.M. Carlson, P. Krasutsky and M.R. Karim. 2003. The in vitro Antifungual Activities of Polyethyleneimine Derivatives of Triterpenoid Compounds against Human Pathogenic Fungi. Abstracts: 103rd General Meeting, American Society for Microbiology, F-086: 288.
  • M.R. Olson, M.C. THompson, M.Gillespie and M.R. Karim. 2003. Cell Cycle Analysis of Glycoprotein Expression in Herpes Simplex Virus II-Infected Cells. Abstracts: 103rd General Meeting, American Society for Microbiology, S-006:623.
  • Mohammad A. Rashid, Md. Shah Alam Bhuiyan, Mohammad Aslam Hossain, Mohammad Abdul Quader, Mohammad Tawhidul Haque Nutan and M. Reza-ul (Raj) Karim. 2002 (+) – USNIC ACID, A ANTIMICROBIAL AGENT FROM PARMELLA KAMTSCHANDALIS. Pakistan Journal of Microbiology, 1 (1), 25-28
  • Muhammad Amjad, Sahana Urooz Kazmi, M. Reza-ul (Raj) Karim and Muhammad Shafi Qureshi. 2002. C-Reactive Protein and Proinflamatory Cytokines in the Pathogensis of Gastroduodenal Ulcer and Helicobacter pylori infection. Pakistan Journal of Microbiology, 1(2): 55-60
  • Amjad, Muhammad, Michael A. Gillespie, Robert M. Carlson, and M. Reza-ul Karim. 2001. Flow Cytometric Evaluation of Antiviral Agents against Human Herpes Virus 6. Microbiol. Immunol., 45(3), 233-240
  • M. Amjad, K.U. Kazmi, SM Qureshi, M. Reza-ul Karim. 2001. Inhibitory effect of IL-4 on the production of IL-1ß and TNF-a by gastric mononuclear cells of Helicobacter pylori infected patients. Irish Journal of Medical Science, 170 (2), 112-116.

Recent Undergraduate Publications:

  • Beukema, Rachel (Faculty Advisor Dr. M. Reza-ul (Raj) Karim). 2003. The Effect of Different Sera at Various concentrations on cell viability. Proceedings of the National Conference of Undergraduate Research (NCUR), Page 1-6.
  • Burmeister, McKenzi (Faculty Advisor Dr. M. Reza-ul (Raj) Karim). 2003. Comparative Long Term Analysis for the Survival Rates of Three Established Cell Lines: Vero, L929 and BHK-21. Proceedings of the National Conference on Undergraduate Research (NCUR). Page 1-7.
  • Klatt, Nichole R. and Welty, Jody L. (Faculty Advisor Dr. M. Reza-ul (Raj) Karim). 2003. Inhibitory Effects of Tea Plant Camellia sinensis Extracts Against Bacteria, Yeast, and Herpes Simplex Virus Type II. Proceedings of the National Council of Undergraduate Research. Page 1-8.

Teaches:

BIOL 1097 Freshman Seminar: Food Preservation, Sanitation, and Handling
BIOL 2961 Introduction to Veterinary Medicine

BIOL 3998 Seminar II
BIOL 4501 Microbiology
BIOL 5511 Virology
BIOL 5513 Experimental Immunology

Recent UROP student projects:

  • Rachel Beukema. 2005. Cell Cycle Stage and Interferon- a Production by HSV-1 and HSV-2 Infected HEP-2 Cells Treated with Betulin.

  • Sean Curry. 2005. When We Eat, Which Bacteria Should We Feed

  • Amanda Feyma. 2005.  Synthesis and Biological Evaluation of New Boronic Acid Based Molecules as Antibacterials

  • Brian Kram. 2005.  Electromagnetic Fields and the Activity of DNA Repair Mechanisms in Serratia marcescens.

  • Munir M. Mosaheb. 2005.  In vitro Effects of Betulin, Betulinic acid and ß -Cyclodextrin Alone and in Combination against HSV-1 and HSV-2 Infection in Vero Cells.

  • Steven Skolasinski. 2005.  Antimicrobial Properties of Epidermal Mucous on Fish Native to the Lake Superior Region.





Last Updated Wednesday, October 25, 2006 9:39 AM