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ILSC Monthly Seminar: Thursday, October 18, 2012


January: Michael Taylor
February: Marna Yandeau-Nelson
March: Paul Lockman
April: Martin Gruebele


January: David D. Thomas
February: Elizabeth Austin-Minor
March: Juliette Lecomte
April: David Millar
May: Lukas Tamm
September: David Millar
September: Dongping Zhong
October: Jonathan V. Rocheleau
November: Yevgenya Grinblat
December: Michael Graner


January: Clay Carter
February (a): Anne Kenworthy
February (b): Jennifer Liang
March: Joe Johnson
April: Marco Ciufolini
May: Gary Pielak
October: Matthew Andrews
December: Andrew Skildum


November: Rui Wang
October: Marshall Hampton

Revealing Pancreatic Islet Molecular Physiology Using Quantitative Fluorescence Microscopy

Speaker: Dr. Jonathan V. Rocheleau;
Institute of Biomaterials and Biomedical Engineering, University of Toronto, Canada
Time/Place: Thursday, Oct. 18, 2012; 3:00 PM / 130 SMed
Host: Erin Sheets (edsheets@d.umn.edu; x6046)

Abstract: Diabetes is increasingly becoming an epidemic due to our aging population. Central to progression of this disease is the pancreatic islet, a micro-organ responsible for the regulated secretion of insulin. Understanding the mechanisms of pancreatic islet function and survival are critical to the development of therapies to treat diabetes. Due to complexity of the organ as well as the small amount of available tissue, traditional biochemical assays are limited in their ability to dissect islet physiology. Our strategy is to develop and combine biomedical engineering and biophysical tools. This seminar describes our efforts using microfluidic devices and quantitative fluorescence microscopy. The goal is to show our research progress as well as introduce methods directly relevant to many areas of biomedical and tissue engineering.

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