Toxicology Graduate Program

Curriculum

This University-wide program provides comprehensive training in the broad scope of toxicology. Toxicology, the science of poisons, is devoted to identifying and characterizing the risk associated with exposures to potential noxious agents in our environment. Although most chemical agents at sufficiently large doses may be toxic, not all present a significant risk to human health, environmental organisms, or ecosystems. Accordingly, the essence of the science of toxicology is defining the line that distinguishes a risk from a residue. This requires scientific expertise in analytical and environmental chemistry, biology, and mathematics. Advanced courses and research are also available in subdisciplines such as human health risk assessment; epidemiology; environmental chemistry and engineering; ecotoxicology; food additives and nutritional toxicology; biochemical and physiological mechanisms; histopathology; diagnostic and analytical toxicology; drug metabolism; chemical carcinogenesis; behavioral toxicology; veterinary toxicology; and the toxicity of noxious agents to various organ systems (e.g., nervous, heart, liver, kidneys).

Toxicology Courses offered:

TOXICOLOGY (TXCL)

TXCL 5000. Directed Research in Toxicology.

(1.0-4.0 cr; prereq #; Pass/Fail only)

Special project that addresses specific issue in toxicology. Under
guidance of faculty member.

TXCL 5011. Principles of Toxicology.

(2.0 cr; prereq Grad txcl major or #; A-F only)

Introduction to fundamentals of poisoning in individuals and the
environment, assessment of potential health hazards, and application of
toxicology in various professional careers.

TXCL 5195. Veterinary Toxicology.

(3.0 cr; prereq Grad student or #; A-F only)

Toxicology of minerals, pesticides, venoms, and various toxins.
Identification of poisonous plants. Recognition, diagnosis, and
treatment of animal poisons.

TXCL 5545. Introduction to Regulatory Medicine.
Draft syllabus for Spring 2008
(2.0-4.0 cr; prereq Grad student or #; A-F only)

Explanation of products requiring pre-market approval and those that
may be marketed without approval. Post-market surveillance. Adverse
reactions, removal of product from market.

TXCL 8012. Advanced Toxicology I.

(3.0 cr; prereq [Duluth: 5011, Chem 4341 or #]; [TC: 5011 or BioC 4331,
PubH 5104 or #]; A-F only)

Absorption, distribution, metabolism, and excretion of xenobiotics;
toxicokinetics; mechanisms of toxicity or specific classes of chemical
agents.

TXCL 8013. Advanced Toxicology II.

(3.0 cr; prereq [Duluth: 8012, Chem 4342, Phsl 5601 or #]; [TC: 8012,
BioC 4332, Phsl 5062 or Phsl 6101 or #]; A-F only)

Kinetic and dynamic determinants of target organ toxicity; pathological
alterations in structure/function relationships for major target organ
systems; mechanisms of mutagenesis, carcinogenesis, and teratogenesis.

TXCL 8100. Investigative Toxicology.

(1.0 cr; prereq 8013 or #; A-F only)

Evaluating toxicology research issues and literature.

TXCL 8333. FTE: Master's.

(1.0 cr; prereq Master's student, adviser and DGS consent)

TXCL 8444. FTE: Doctoral.

(1.0 cr; prereq Doctoral student, adviser and DGS consent)

TXCL 8666. Doctoral Pre-Thesis Credits.

(1.0-18.0 cr; prereq Max 18 cr per semester or summer; doctoral student
who has not passed prelim oral)

TXCL 8777. Thesis Credits: Master's.

(1.0-18.0 cr; prereq Max 18 cr per semester or summer; 10 cr total
required (Plan A only))

TXCL 8888. Thesis Credits: Doctoral.

(1.0-24.0 cr; prereq Max 18 cr per semester or summer; 24 cr required)