Oxygen supply: development of the cardiovascular and respiratory systems.
Redirecting blood flow in newborn mammals. Morphology and physiology of circulatory organs in insects.

Discussion of "Developmental plasticity of the cardiovascular system of fish, with special reference to the zebrafish" by B. Pelster --> pdf

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Acquiring energy: development of the digestive tract, feeding, metabolism.
Regional specification of the digestive tube. Molecular mechanisms of liver and pancreas development.

Discussion of a paper on pancreas development: "The IIIb isoform of fibroblast growth factor receptor 2 is reqired for ..." by M.-A. Pulkkinen et al. --> pdf

Sensing the environment: development of nervous systems and sensory organs. Nervous system development in zebrafish. Eye development in chicken embryos.

Guest lecture 1 pm: Janet Fitzakerley (UMD School of Mecicine) - Inner ear development (--> pdf "Gradients of neurotrophins, ion channels and tuning in the cochlea" by R.L. Davis = review article related to topic of Janet's talk)

Getting around: muscle development and animal movement - part 1
Neuromuscular development in vertebrates. Vascular patterning in the tetrapod limb. Larval-adult changes in muscle morphology and function in insects.

Getting around: muscle development and animal movement - part 2
Neuromuscular development in vertebrates. Vascular patterning in the tetrapod limb. Larval-adult changes in muscle morphology and function in insects.

Discussion of a paper on chick eye development: : "Light-dependent development of asymmetry in the ipsilateral and contralateral thalamofugal visual projections of the chick" by M. Koshiba et al. --> pdf

Glands and hormones: endocrine regulation of development. Hormonal control of metamorphosis in amphibians. Hormonal control of insect development and metamorphosis. Sexual differentiation in amphibians.

Discussion of: "Broad specifies pupal development and mediates the 'status quo' action of juvenile hormone on the pupal-adult transformation in Drosophila and Manduca" by Zhou & Riddiford --> pdf

 Student presentations start:

Jeffrey Wright: 'Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis' by J.R. Hove et al. -->pdf

Jeffery Fabian: 'The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis' by Garkavtsev I. et al. --> pdf

Critiques prepared by: Jessica Nieuboer & Daryn Collins

Katharine Brauch: 'Isoform-specific changes in scleral TGF-b expression and the regulation of collagen synthesis during myopia progression' by A. Jobling et al. --> pdf

Justin Spanier: 'A feedback mechanism regulates monoallelic odorant receptor expression' by J.W. Lewcock & R.R. Reed --> pdf

Critiques prepared by: Heidi Estby & Karen Lee

 Karen Lee: 'Morphogenesis of chicken liver: identification of localized growth zones and the role of [beta]-catenin/Wnt in size regulation' by S. Suksaweang et al. --> pdf

Tammy Krzoska: 'Abnormal blood vessel development in mice lacking presenilin-1' by M. Nakajima et al. --> pdf

Critiques prepared by: Jeffery Fabian & Katharine Brauch

 Heidi Estby: 'Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae' by Joshua M.H. Hall et al. --> pdf

Critique prepared by: Jeffrey Wright

12 noon / LSci 185: Seminar presented by one of the candidates for the cell biology faculty position in the Biology Dept - please attend

1 pm / Kirby Plaza 312 -> Jessica Nieuwboer: 'The activation level of the TNF family receptor, Edar, determines cusp number and tooth number during tooth development' by A.S. Tucker et al. --> pdf

Critiques prepared by: Justin Spanier & Jeffery Fabian

Distribution of topics for final paper

Literature for final:

--> pdf1, pdf2, pdf3, pdf4, pdf5, pdf6, pdf7, pdf8.

Daryn Collins: 'Functional role of growth/differentiation factor 5 in chondrogenesis of limb mesenchymal cells' by C.M. Coleman & R.S. Tuan --> pdf

Critique prepared by: Tammy Krzoska

Lecture: Phenotypic plasticity - Control of development by environmental conditions. Seasonal and nutritional polyphenism in insects. Endocrine disruption by water contaminants. Parasite effects on insect and frog development.

Course evaluation & final discussion