Study Guide for Chem 2222

1A

Introduction. Basic Operations in Chemical Analysis.

• Nature of quantitative analysis
• Course objectives
• Steps in an analysis
• The balance and weighing in analytical chemistry
  • Mass, weight, balance
  • Analytical balances (classification, construction, operational features)
  • Errors in weighing

Ch 1, Introduction.

Problem set 1. Chemical Calculations, Stoichiometry and Equilibrium.

Tools and Operations.

• Keeping a laboratory notebook
• Weighing samples
• Specifications, use and care of volumetric glassware

1B

Review of Chemical Calculations. Concentration and Stoichiometry

Review I. Chemical calculations.

Ch 3, review of some basic concepts. Work through all examples in Ch 3, and starred exercises at end of chapter. See especially Ch 3A-C, and problems #1-38.

Self test on chemical calculations. Try this quiz before the lecture to help you identify areas you need to review.

Operations and Calculations in Titrimetric Analysis

Titrimetric Analysis I. Standard solutions and calculations for acid-base titrations. Lecture demonstration on acid-base titration.

Ch 11 "Titrimetric Methods of Analysis", including starred problems at the end of the chapter. Ch 27, pp 721-723 and sections C-1 to C-8 on neutralization titrations.

Problem set 2. Calculations in Titrimetric Analysis.

Titrimetric Analysis II. Calculations in titrimetric analysis.

Treatment of Analytical Data and Error Analysis.

Data Treatment I . Part IA. Nature of errors in chemical analysis. Precision and accuracy, systematic and random errors. Treatment of data with random errors. Normal distribution, standard deviation.

Ch 5, "Errors in Chemical Analysis", all sections, starred problems.

Ch 6, "Random Errors", all sections, starred problems.

Problem Set 3. Data Treatment.

Statistics on your calculator. You should be able to compute common statistical data using your calculator. There will be no class instruction on calculator usage. Lost your manual? User manuals may be available on the manufacturer's website. If yours is from Texas Instruments, go to their Downloads page.

Ch 7, Statistical Analysis", sections A-C, problems #1, 2, 4, 6, 11, 13; remaining starred problems #1-16.

Data Treatment II. Calibration curves and linear least squares analysis.

Using Excel in analytical chemistry

• Examples for successive approximations and pooled standard deviation (Excel).
• Calibration curves and least squares.
  • Calibration Curves and Regression Analysis (pdf)
  • Using Excel for Calibration Curves and Regression Estimates (Excel)

Ch 7, section D. Problem #19.

Learn to use spreadsheets in analytical chemistry. Complete the following exercises over the next week. In addition to the exercises in your text, you may find the Microsoft training site useful. See Training for Microsoft Excel.

• Basic operations. Skoog, Ch. 2, section J.
• Mean and standard deviation. Ch 5, section B.
• Computing standard deviation. Ch 6, section B.
• Computing pooled standard deviation. Ch 6, section B.
• Least squares analysis. Ch 7, section D. The section on Using LINEST may be omitted in favor of using the Regression Tool in Excel.

Includes all topics in Unit 1, except regression analysis (Ch 7, section D)

Review Notes