Chemistry 4242, Instrumental Analysis Lecture, Course Syllabus, Spring 2005

Chem 4242 (3 credits) deals with fundamental aspects of instrumental methods of chemical analysis.  It is required for the B.S. degrees in Chemistry and in Biochemistry and Molecular Biology. Chemistry majors should also register for the laboratory course Chem 4243. All students should complete Quantitative Analysis (2222) and Physical Chemistry (5611 or 5622) prior to registering for this course.

General Information

Instructor:

D. Poe; 726-7217; dpoe@d.umn.edu; 333 Chem; Office Hrs 9-10 am MW. Home page:  www.d.umn.edu/~dpoe

Class Meetings:

1:00-1:50 MWF, 251Chem.

Text:

Skoog, Holler and Nieman, Principles of Instrumental Analysis, fifth edition, Saunders, 1998.

Computing Resources:

You should have access to a spreadsheet such as Microsoft Excel. Additional software needed for this course can be obtained as free downloads.

Bulletin Description

4242. INSTRUMENTAL ANALYSIS. (3.0 cr; Prereq-2222, 4632 or 4642; A-F or Aud, spring, every year). Theory and applications of instrumental methods of chemical analysis, including electrochemistry, spectroscopy, and separations.

Goals

Fundamental aspects of instrumental methods of analysis, including sensitivity, instrumental response characteristics, noise and precision, will be examined, and some of the major electrochemical, chromatographic, and spectroscopic methods will be studied.  The basic principles on which each method is based, as well as instrumental design, common chemical applications, and the strengths and limitations of various techniques will be examined.

Topics

  1. General Aspects of Instrumental Analysis
    1. Introduction, Performance, Calibration
    2. Signals and Noise
  2. Spectroscopy I. Fundamentals and Instrumentation
    1. Fundamentals
    2. Instrumentation for Optical Spectroscopy
  3. Spectroscopy II. Atomic Spectroscopy
    1. Atomic Spectroscopy
    2. Atomic Absorption Spectroscopy
    3. Atomic Emission Spectroscopy
    4. Atomic Mass Spectroscopy
  4. Spectroscopy III. Molecular Spectroscopy
    1. Molecular Absorption Spectrophotometry
    2. Molecular Fluorescence Spectroscopy
    3. Molecular Mass Spectroscopy
    4. Other
  5. Electrochemistry
    1. Fundamentals
    2. Potentiometry
    3. Coulometry
    4. Voltammetry
  6. Separations
    1. Fundamentals
    2. Gas Chromatography
    3. Liquid Chromatography
    4. Electrophoresis
    5. Other
  7. Hyphenated Methods
    1. GC-MS, LC-MS
    2. Other

Final Exam:  Monday, May 9, 12:00-1:55 pm.

Evaluation

Examinations and quizzes (60-80%); homework, reports, participation (20-40%).

Access for Students with Disabilities

Individuals who have any disability, either permanent or temporary, which might affect their ability to perform in this class are encouraged to inform the instructor at the start of the quarter.  Adaptation of methods, materials, or testing may be made as required to afford equity in the classroom.