Chem 4242, Spring 2005

Part I. General Aspects of Instrumental Analysis

Topic	Lecture Notes and Reference Materials	Periods	Reading/Study Assignment (SHN = Skoog, Holler, Nieman, 5e)
1A. Introduction, Performance, Calibration	Introduction (ppt). General aspects, performance characteristics, calibration methods. Reference materials Discussion on calibration curves in chemical analysis. See SHN Appendix 1 for a more extensive discussion. Sample Excel spreadsheet for calibration curves.	2	SHN Ch 1, Introduction. Focus on sections 1D (Selecting a method based on performance characteristics) and 1E (calibration methods). Problem Set 1.
1B. Signals and Noise	*Signals and Noise (ppt).* Signal-to-noise ratio, ways to decrease noise, response characteristics of electronic instruments.	1	SHN Ch 5, Signals and Noise, with special emphasis on sections A and B. See also Notes and Corrections to Text
	Review of Data Treatment. Errors, accuracy, and precision; statistical treatment of random errors, confidence limits; propagation of errors in calculations; linear least squares and calibrations curves.	0	Please review the topics in Appendix 1 on your own, and test yourself on these exercises: App 1, #15,19,20,23.