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Göran Hellekant, D.V.M., Ph.D.
Professor
Department of Physiology and Pharmacology
Medical School Duluth
347 SMed
1035 University Drive
Duluth, MN 55812
Office Phone: (218) 726-6669
Email: ghelleka@d.umn.edu

Research Description
He has 135 printed publications and his research activities consist of taste physiology, sweeteners and sweetness, oral circulation, and salivation. The research uses a large number of animal models both for electrophysiology and behavior. Present projects study how the ability to taste sweet and bitter is affected by presence or absence of sweet and bitter receptors in the taste buds. We are also researching what kind of intracellular links that are involved in sweet and bitter taste. Another project uses an intensely sweet protein to increase our understanding on how sweet compounds stimulate our taste buds. The related question on how this message from the taste buds is coded has been another focus of our research.

Education

BVS,Veterinary Medicine, Royal Veterinary College, Stockholm, Sweden, 1961
PhD, DVM, Physiology, Royal Veterinary College, Stockholm, Sweden, 1965
Postdoctoral, Neurophysiology, Massachusetts Instit. of Technology, Boston, MA, 1966-1967
Docent, Physiology, Royal Veterinary College, Stockholm, Sweden, 1967

Professional Experience
Professor at the Department of Physiology, Royal Veterinary College (Kungliga Veterinärhögskolan), Sweden, 1974
Director of Research and Chairman of the Department of Biomedicine at the National Defense Research Institute (Försvarets Forskningsanstalt), Stockholm, Sweden, 1978
Professor at the Department of Animal Health and Biomedical Sciences, University of Wisconsin, Madison, Wisconsin, USA. Affiliate Scientist at Wisconsin Regional Primate Center, Madison, 1979-2005
Professor at the Department of Physiology and Pharmacology, Medical School, University of Minnesota, Duluth, 2005-present

Honors, Fellowships and Awards
1964 The Gålö Foundation Prize
1966-67 Postdoctoral Fellowship at MIT, Boston, Massachusetts
1971 Flohrmanska belöningen
1979 The Japan Society for Promotion of Science
1979 IUPS Commission of Olfaction and Taste
1993 Asahi University, Gifu, Japan. Honorary recognition
1996 Scientific Committee of the First International Symposium on Sweeteners
1998 Scientific Committee of the Second International Symposium on Sweeteners
2005 State of Wisconsin, Certificate of Commendation for 26 years of Public Service

Recent Publications

Ninomiya, Y., Nakashima, K., Fukuda, A., Nishino, H., Sugimura, T., Hino, A.. Danilova, V., Hellekant, G. Responses to umami substances in taste bud cells innervated by the chorda tympani and glossopharyngeal nerves. J. Nutr. 2000. 130. 950S-953S.
Danilova, V., and Hellekant, G., The taste of ethanol in a primate model II: Glossopharyngeal nerve response in Macaca mulatta. Alcohol. 2000. 21. 259-269.
Neira, M., Danilova, V., Hellekant, G., and Azen, E. A.. A new gene (rmSTG) specific for taste buds found by laser capture microdissection. Mamm Genome. 2001. 12. 60-66.
Danilova , V., Hellekant, G., Oral sensation of ethanol in a primate model III.: Responses in the lingual branch of the trigeminal nerve of Macaca mulatta. Alcohol. 2002. 26. 3-16.
Danilova, V., Danilov, Y, Roberts, T. Tinti, J-M., Nofre, C., and Hellekant, G., The sense of taste in a New World monkey, the common marmoset: recordings from the chorda tympani and glossopharyngeal nerves.. J. Neurophysiology. 2002. 88. 579-594
He, W., Danilova, V.,Zou, S., Hellekant, G., Max, M., Margolskee, R. F., Damak, S. Partial Rescue of Taste Responses of alpha-Gustducin Null Mice by Transgenic Expression of alpha-Transducin. Chem. Senses. 2002. 27. 719-727.
Danilova , V., Hellekant, G., Comparison of the responses of the chorda tympani and glossopharyngeal nerves to taste stimuli in C57BL/6J mice. BMC Neuroscience. 2003. 4:5.
Jin Z., Danilova V., Assadi-Porter F. M., Aceti D. J. , Markley J. L. and Hellekant G. Critical Regions for the Sweet Taste of Brazzein. FEBs letter. 2003. 544, 33-37.
Jin Z., Danilova V., Assadi-Porter F. M., Aceti D. J. , Markley J. L. and Hellekant G. Moneky electrophysiological and human psychophysical responses to the sweet protein brazzein: Delineating brazzein sweetness. Chem. Senses. 2003. 28. 491-498.
Hladik C. M., Pasquet P., Danilova V., Hellekant G. The evolution of taste perception : psychophysics and taste nerves tell the same story in human and non-human primates. Comptes rendus. 2003. 2. 281-287.
Schilling A.,Danilova V., and Hellekant G. Behavioral study in the gray mouse lemur (Microcebus murinus) using compounds considered sweet by humans. Am. J. Prim. 2004. 62. 43-48.
Danilova, V. And Hellekant, G., Sense of taste in a New World monkey, the common marmoset. II. Link between behavior and nerve activity. J. Neurophysiology. 2004. 92. 1067-76.
Hellekant, G., and Danilova , V., Coding of sweet and bitter taste: lessons from the common marmoset, Callithrix jacchus jacchus. Primatologie. 2004. 6. 47-85.
Hellekant, G., and Danilova , V., Brazzein, a small sweet protein: discovery and physiological studies. Chem. Senses, suppl. 1, i88-i89. 2005.
Schilling A., Danilova V., and Hellekant, G., Le prosimien, Microcebus murinus, percoit-il les substances sucrees diff’eremment des autre primates? Primatologie. 2004. 6. 87-99.
Finger, T. E., Danilova, V. Barrows, B., Bartel D., Vigers, A. J., Stone, L., Hellekant, G., and Kinnamon, S. A. ATP Signaling Is Crucial For Communication From Taste Buds To Gustatory Nerves. Science, 2005, Dec 2. 1495-1498.
Danilova, V., Hellekant, G. Elucidating coding of taste qualities with the taste modifier miraculin in the common marmoset. Brain Res. Bull. 2006. 68. 315-321.
Danilova, V., Damak, S., Margolskee, R. F., Hellekant, G. Taste response to sweet stimuli in alpha-Gustducin Knockout and Wild Type Mice. Chem. Senses. 2006. 31. 573 - 580.
Walters, D. E, Hellekant .G., Interactions of the Sweet Protein Brazzein with the Sweet Taste Receptor. .J Agric. Food Chem. 11/23. 2006