IBS 8012 Spring 2009

Integrated Evolutionary Processes

 

Dr. Julie R. Etterson

 

 

Office:

153B SSB 

Lab:

180 SSB 

Phone:

726-8110

Email: 

jetterso@d.umn.edu

Class hours:

8:00 – 9:50 F, 207A SSB

Readings:

Listed on syllabus and web page

Office hours:

9:00-10:00 T or by appointment

 

Purpose:

 

This course will present current thinking on the mechanisms and consequences of evolution at all levels of biological organization from the molecule to the ecosystem

.  

Class format:

8:00-8:10

Essay question and reading from the primary literature (QQQ)

 

8:10-8:25

Student presentation on reading

 

8:25-8:50

Small group discussion of the reading

 

8:50-9:00

Large group wrap up

 

9:00-9:10

Break

 

9:10-9:50

Lecture

 

Lectures:

Lecture material will be drawn from the primary literature.  PowerPoint presentations will be handed out at the beginning of each lecture and will include all tables and figures.

 

Essay Questions:

Quick Quiz Questions (QQQ) will consist of 3-5 five essay questions on the weekly reading assignment will be posted on the web in advance of class.  Students are expected to prepare answers to each question and will be expected to write a 10-minute essay in class on one of the QQQ prior to the student presentation on the reading and discussion.  Essays should be written in paragraph form and provide specific examples from the assigned reading to justify your answer.

 

Journal article presentation and discussions:

A pair of students will be assigned to present each journal article and facilitate the small-group and large-group discussions. The students will give a brief PowerPoint presentation (15-20 min).  Presentations should include the following elements:

 

  • Objectives of the paper
  • The study system (pictures of organisms are always nice)
  • Methodological approach
  • Major results (include figures and tables from the paper)
  • Major conclusions

 

The presentation should conclude with a list of thought-provoking questions (5-10) that will be discussed in small groups (~25 min).  The final question on this list should always be “How does this paper illustrate the integrative nature of evolutionary processes?”  In the last 10 minutes of class, the assigned pair of students will facilitate discussion of any remaining issues and summarize the major points. 

 

Students will be graded on:

  • clarity of presentation of the major results and conclusions
  • quality of their discussion questions
  • ability to facilitate the group discussion and summarize the major points

 

Research paper:

The goal of this assignment is for you to explore how your thesis question relates to the major themes of this course.  For some of you, the relationship will be obvious because your research question is inherently evolutionary.  For others, I encourage you to think about how evolutionary processes underlie your research question.  In either case, I would like you write a review paper (~15-20 pages double spaced not including the literature cited, 1-inch margins, 12-point font) that explores how evolutionary processes integrate aspects of your field of study.  You should include evolutionary hypotheses and a section that describes experiments to test these hypotheses.  The first draft of your paper will be reviewed by me and two of your peers and draft will be due at the end of the semester.

 

Peer evaluations: 

Peer evaluation is an essential component of a scientific career.  Scientists need to be able to competently evaluate the work of others and learn how to improve their own work by incorporating constructive criticisms.  A scientist receives peer evaluations in many aspects of their work including: grant proposals, manuscripts, delivery of courses, annual performance reviews, and overall evaluations of their contributions of their field through the process of tenure and promotion.  Learning how to provide and utilize constructive criticism is an extremely important but often neglected part of graduate education.  As a part of this course, you will be asked to provide an anonymous peer review on the first draft of a research paper of two of your classmates.  You will also receive three reviews, two from students and one from me.  You will be expected to take the suggestions of these reviews into account in the final draft of your research paper. 

 

Class participation: 

Active participation is expected during lectures and discussions and will be considered in the computation of your final grade.  Attendance is mandatory

 

Grading: 

Grading will be based on weekly in-class essay quizzes, journal article presentations, one research paper on the topic of your choice, peer evaluation of classmates’ research papers, and participation in lecture and discussion.

 

 

Assignment

Points per assignment

% of final grade

Weekly essay questions (15)

10

15

Journal article presentation (2)

50

20

First draft of research paper

50

20

Peer evaluation of research paper (2)

50

15

Final draft of research paper

50

20

Class participation

50

10


Tentative Syllabus

 

 

Week

 

Day

 

Lecture Topic

 

TENTATIVE

Assigned Reading

 

Student Presentations

 

Other assignments

1

1/23

Evolution as an integrating process

 

none

 

Variation – a central concept

2

1/30

Origins of variation

Williamson 2003. Adaptation in the env Gene of HIV-1 and Evolutionary Theories of Disease Progression Mol. Biol. Evol. 20(8):1318-1325 

FYI Levy et al. 2007. The diploid genome sequence of an individual humna PLoS Biology 5:2113-3144

QQQ

Example of a good essay

Katie, Megan and Lauren

 

3

2/6

Phylogeny construction

Gu et al. 2003. Role of duplicate genes in genetic robustness against null mutations. Nature 421:63-66

QQQ

Adam, Janel, and Lee

 

4

2/13

Significance of variation

Meyer and Schartl 1999. Gene and genome duplications in vertebrates: the one-to-four
(-to-eight in fish) rule and the evolution of novel gene functions

QQQ

Tommy, Elise and Ashley

 

Integrating from genes to phenotypes in nature

5

2/20

What is Evo-devo?

Anderson et al. 2005. The latitudinal cline in the In(3R)Payne inversion polymorphism has shifted in the last 20 years in Australian Drosophila melanogaster populations. Molecular Ecology 14: 851–858

QQQ

Jennifer, Janel and Ada

 

6

2/27

Open discussion about your thesis topic and is relationship to evolutionary processes

Abzhanov et al. 2006. The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches

QQQ

Annie, Adam, and Elise

 

7

3/6

 

Open discussion about your thesis topic and is relationship to evolutionary processes

Caceres et al. 2003. Elevated gene expression levels distinguish human from non-human primate brains. PNAS 100:13030-13035

QQQ

Chelsey and Katie

 

8

3/13

Plasticity

Beldade et al. 2002. Developmental constraints versus flexibility in morphological evolution. Nature 416:844-847

QQQ

Megan and Tommy

Turn in tentative research paper topics

 

3/20

Spring Break

 

 

 

                                                                       Life history

9

3/27

Life history trade-offs

Galloway and Etterson. 2007. Transgenerational plasticity is adaptive in the wild.  Science 318:1134-1136

QQQ

Amanda and Ada

Turn in outline and bibliography

10

3/3

Evolution and behavior

Heath et al. 2003. Rapid evolution of egg size in captive salmon. Science 299:1738-1740

QQQ

 

Carly and Sarah

 Link to critical thinking guide

11

4/10

The evolution of aging

Pfennig. 1999. Cannibalistic tadpoles that pose the greatest threat to kin are most likely to discriminate kin. Proc. R. Soc. Lond. B 266:57-61

QQQ

Jennifer and Rebecca

12

4/17

Evolution in communities

Hughes, K.A. et al. 2002.  A test of the evolutionary theories of aging. PNAS 99:14286

QQQ

Chelsey and Amanda

Turn in first draft for peer review 

Communities and ecosystems

13

4/24

 

Turn around peer reviews

Grant and Grant. 2006. Evolution of character displacement in Darwin’s finches. Science 313:224-226.

QQQ

Carly and Annie

Peer evaluations due

Benos et al. 2003. How to review a paperAdvan Physiol Educ 27:47-52, 2003.

Reviewer Guidelines to follow modified from ESA

14

5/1

Evolution and ecosystem properties

Hairston et al. 1999. Rapid evolution revealed by dormant eggs. Nature 401:446

Weider et al. 1997. Long-Term Genetic Shifts in a Microcrustacean Egg Bank Associated with Anthropogenic
Changes in the Lake Constance Ecosystem
Proceedings: Biological Sciences 264:1613-1618

QQQ

Sarah and Ashley

 

15

5/8

 

 Course evaluations

Schweitzer et al. 2004. Genetically based trait in a dominant tree affects ecosystem processes.  Ecology Letters 7: 127-134

QQQ

Lauren, Lee and Rebecca

Example of a letter that responds to reviewer comments

 

Final draft of research paper due

 

 

Academic Dishonesty:

Academic dishonesty tarnishes UMD's reputation and discredits the accomplishments of students. UMD is committed to providing students every possible opportunity to grow in mind and spirit. This pledge can only be redeemed in an environment of trust, honesty, and fairness. As a result, academic dishonesty is regarded as a serious offense by all members of the academic community. In keeping with this ideal, this course will adhere to UMD's Student Academic Integrity Policy, which can be found at www.d.umn.edu/assl/conduct/integrity. This policy sanctions students engaging in academic dishonesty with penalties up to and including expulsion from the university for repeat offenders.

 

Student Conduct Code: 

The instructor will enforce and students are expected to follow the University's Student Conduct Code (http://www.d.umn.edu/assl/conduct/code). Appropriate classroom conduct promotes an environment of academic achievement and integrity. Disruptive classroom behavior that substantially or repeatedly interrupts either the instructor's ability to teach, or student learning, is prohibited. Disruptive behavior includes inappropriate use of technology in the classroom. Examples include ringing cell phones, text-messaging, watching videos, playing computer games, doing email, or surfing the Internet on your computer instead of note-taking or other instructor-sanctioned activities.

 

Access for Students with Disabilities:

Individuals who have any disability, either permanent or temporary, which might affect their ability to perform in this class are encouraged to inform the instructor at the start of the quarter. Methods, materials or testing may be modified to provide for equitable participation.

 

Promotion of Bias-free Instruction:

The University of Minnesota is committed to the policy that all of its students shall have equal educational opportunities. The University expressly forbids discrimination on the basis of race, color, gender, sexual orientation, disability, veteran's status, ethnicity, religion, creed, national origin or marital status. If you believe that your Biology instructor has not followed this policy, you are invited to bring this to the attention of the Biology Department Head (211 Life Science; 726-7263) or the Associate Dean of the College of Science and Engineering (140 Engineering; 26-7585). Your conference will be kept confidential.