(Quick Quiz Questions)

Caceres et al. 2003. Elevated gene expression levels distinguish human from non-human primate brains. PNAS 100:13030-13035 

  1. How do structural differences in human and primate brains compare to differences in gene expression?
  2. Why do you think the differences between gene expression in chimp and human hearts and livers were much less dramatic?
  3. Why do you think it so important to have multiple lines of evidence to support the conclusions of this paper?
  4. If you have unlimited resources, can you think of another way that investigators could check for biases in expression due to differences in sequences among the species in this study?
  5. What new hypotheses are generated from the results of this work?