2015 Antineoplastics

RESISTANCE

Resistance to cancer chemotherapeutic drugs is a major limitation to treatment.  PRIMARY RESISTANCE occurs when some inherent characteristic of the cancer cells prevents the drugs from working;  ACQUIRED RESISTANCE occurs when cancer cells become resistant during treatment.  MULTIDRUG RESISTANCE is particularly problematic; this occurs when tumour cells become cross-resistant to a wide range of chemically dissimilar agents after exposure to a SINGLE (typically natural product) drug.

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Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 11-apr-15 9:39 AM