2014 Inner Ear Physiology

Stereocilia damage

Normal organ of Corti

Scanning electron micrograph showing the normal organization of the organ of Corti. View is of the apical membrane of the single row of IHCs (top) and 3 rows of OHC (bottom). Notice the orderly arrangement of stereocilia.

Noise induced hearing loss

Disruption of IHC stereocilia and loss of OHC in the basal turn of the cochlea following noise exposure (90 dBA noise for 8 hours) 6 months earlier. This damage produced a profound hearing loss.

Kanamycin damage

Disruption of OHC stereocilia following administration of the aminoglycoside antibiotic kanamycin. Depending upon dose, drug administration can cause either a temporary or permanent threshold shift.

Email: Dr. Janet Fitzakerley | ©2014 University of Minnesota Medical School Duluth | Last modified: 15-feb-14 9:04 PM