mTOR Inhibitors: EVEROLIMUS, TEMSIROLIMUS
Therapeutic Uses
- mTOR inhibitors are first-line therapies for the treatment of renal cell carcinoma
- mTOR inhibitors may enhance the effects of other antineoplastic therapies, including:
- angiogenesis inhibitors that target VEGF, like BEVACIZUMAB and tyrosine kinase inhibitors (STIs)
- anti-EGFR treatments
- anti-estrogens and aromatase inhibitors
- radiation