mTOR Inhibitors: EVEROLIMUS, TEMSIROLIMUS
Toxicity
- hypersensitivity
- as with other immunosuppressants, increased risk of:
- lymphomas, particularly of the skin
- infection
- angioedema
- kidney arterial and venous thrombosis
- delays in wound healing
- hyperlipidemia
- nephrotoxicity and proteinuria
- male infertility