Prevent DNA synthesis / Antimetabolites / Pyrimidine analogues
B. Pyrimidine analogues
Types
The difference between nucleotide synthesis inhibitors and inhibitors of DNA synthesizing enzymes is a relatively subtle distinction in terms of mechanism!
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Nucleotide synthesis inhibitors: 5-FLUOROURACIL (5-FU), CAPECITABINE
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Inhibitors of DNA synthesizing enzymes: CYTARABINE, GEMCITABINE