2015 Antineoplastics

B. Pyrimidine analogues

Types

The difference between nucleotide synthesis inhibitors and inhibitors of DNA synthesizing enzymes is a relatively subtle distinction in terms of mechanism!
  1. Nucleotide synthesis inhibitors: 5-FLUOROURACIL (5-FU), CAPECITABINE

  2. Inhibitors of DNA synthesizing enzymes: CYTARABINE, GEMCITABINE

Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 11-apr-15 9:39 AM