2015 Antineoplastics

I. Nucleotide synthesis inhibitors

Types (all are antimetabolites)

  1. Folic acid analogues: METHOTREXATE, PEMETREXED, PRALATREXATE
    • LEUCOVORIN (supporting agent used for rescue)

  2. Pyrimidine analogues: 5-FLUOROURACIL (5-FU), CAPECITABINE

  3. Purine anaologues: 6-MERCAPTOPURINE, 6-THIOGUANINE
    • ALLOPURINOL (supporting agent used to prevent hyperuricemia)

 

Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 11-apr-15 9:39 AM