2015 Antineoplastics

A. Folic acid analogues

Types

  1. Nucleotide synthesis inhibitors: METHOTREXATE, PEMETREXED, PRALATREXATE

    • other antifolates are on the market or in development; like PEMETREXED, they are designed to have a higher affinity for the reduced folate carrier and for the formation of polyglutates

  2. Supporting agent: LEUCOVORIN (used for rescue)
Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 11-apr-15 9:39 AM