2015 Antineoplastics

C. PURINE ANALOGUES : 6-MERCAPTOPURINE (6-MP), 6-THIOGUANINE (6-TG)

Toxicity

  • primary toxic effects are on bone marrow

  • anorexia, nausea and vomiting occur in 25% of adults; less often in children

  • as with any drugs used to treat leukemias, can cause TUMOUR LYSIS SYNDROME
Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 11-apr-15 9:39 AM