2015 Antineoplastics

I. Crosslinking agents

Cisplatin functionTypes (by chemical classification)

MECHLORETHAMINE was the 1st alkylating agent to be used clinically. It is a derivative of mustard gas, a chemical warfare agent developed during World War I. Physicians treating soldiers realized that bone marrow suppression was a problem in people who managed to survive the initial vesicant effects.

There are many more alkylating agents than are included on your list of "drugs that you need to know".

Many alkylating agents have specific therapeutic uses e.g.,

Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 11-apr-15 9:39 AM