Disrupt DNA / Crosslinking Agents / Unique properties
Unique properties of various crosslinking agents
-
in addition to the properties that are common to all crosslinking agents, each of these drugs also has some characteristics that make it unique
-
the 5 key drugs to know really well in this class are: MECHLORETHAMINE, CYCLOPHOSPHAMIDE (IFOSFAMIDE), the NITROSOUREAs (CARMUSTINE and LOMUSTINE), and CISPLATIN (CARBOPLATIN, OXALOPLATIN)
- the other drugs have one or two quirky properties that distinguish them from the other drugs in this class