Prevent DNA synthesisDRUGS THAT DISRUPT DNA
Mechanism Types
(there is some overlap among the 3 functional groups)
I. Crosslinking agents
- chemical classes include alkylating agents, natural products (antibiotics) and miscellaneous
II. Intercalating agents
- chemical classes include natural products (anthracyline and other antibiotics)
III. Drugs that cause strand breaks
- chemical classes include natural products (antibiotics and plant alkaloids) and miscellaneous