Drugs that disrupt DNA / Strand breaks
III. Drugs that cause DNA strand breaks
Types (by chemical classification)
-
Antibiotic: BLEOMYCIN
- Plant alkaloids:
- Epipodophyllotoxin: ETOPOSIDE
- Camptothecins: IRINOTECAN/TOPOTECAN (there are other camptothecins in use)
- Alkylating agent: PROCARBAZINE