2015 Antineoplastics

CONTRIBUTING CAUSES OF RESISTANCE TO ANTINEOPLASTIC DRUGS

  1. Poor drug distribution

  2. Sanctuary sites (esp. brain)

  3. Tumour cells not in cycle

  4. Heterogeneity of tumour cells leading to clonal selection

 

 

 

 

Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 11-apr-15 9:39 AM