2015 Antineoplastics

1. Cytokines

The cytokines used for cancer chemotherapy share some common characteristics.  They all have short half-lives, and are not cytotoxic by themselves à they recruit immune cells to do the actual cell kill (which means the immune system has to recognize the tumour cells as foreign).  Despite their human origin, when given as antineoplastics, INTERLEUKIN 2, INTERFERON α and TUMOUR NECROSIS FACTOR α can have serious, even fatal, side effects.
Critical facts icon
Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 11-apr-15 9:39 AM