Target altered protein function / Altered processes
Target altered processes
- as we learn more about intracellular signalling pathway differences between normal and cancer cells, more targets are being identified for antineoplastic cells
- however, in contrast to drugs that target specific mutated/overexpressed proteins or growth factor receptors, drugs that target altered intracellular processes tend to be less selective, and these drugs tend to have a greater number of side effects
- in other words, these drugs tend to have similarities to cytotoxic drugs that simply target rapidly dividing cells