INHIBITORS

INDUCERS

SUBSTRATES

INHIBITORS

INDUCERS

SUBSTRATES

CYP1A2

CYP3A4

cimetidine
ciproflxacin
enoxacin
erythromycin
***fluvoxamine
grepafloxacin
isoniazid
mexiletine
norfloxacin
tacrine
zileuton

barbiturates
carbamazepine
charcoal-broiled foods
lansoprazole
omeprazole
phenytoin
rifampin
smoking

alosetron
amitriptyline
caffeine
clomipramine
clozapine
cyclobenzaprine
grepafloxacin
imipramine
mirtazapine

olanzapine
propranolol
riluzole
ropinirole
R-warfarin
tacrine
theophylline
zileuton

amiodarone
amprenavir
clarithromycin
cyclosporine
danazol
delavirdine
diltazem
efavirenz
erythromycin
ethinylestradiol
fluconazole
fluvoxamine
grapefruit juice
indinavir
itraconazole
ketoconazole
nefazodone
nelfinavir
quinine
***ritonavir
saquinavir
Synercid
troleandomycin
verapamil
zafirlukast

barbiturates
carbamazepine
dexamethasone
efavirenz
ethosuximide
griseofulvin
modafinil
nafcillin
nevirapine
oxcarbazepine
phenytoin
primidone
rifabutin
***rifampin
rifapentine
St. John's wort

alfentanil
alprazolam
amiodipine
amprenavir
atorvastatin
bepridil
buspirone
carbamazepine
cerivastatin
cisapride
citalopram
clarithromycin
clomipramine
corticosteroids
cyclophosphamide
cyclosporine
dapsone
delavirdine
diazepam
diltiazem
disopyramide
dofetilide
donepezil
doxorubicin
efavirenz
erythromycin
ethinylestradiol
etoposide
felodipine
fentanyl
finasteride
ifosfamide
imipramine
indinavir
isradipine
itraconazole
ketoconazole
lansoprazole
loratadine
losartan

lovastatin
methadone
midazolam
mirtazapine
montelukast
nefazodone
nelfinavir
nicardipine
nifedipine
nimodipine
nisoldipine
paclitaxel
pimozide
quetiapine
quinidine
quinine
repaglinide
refabutin
ritonavir
saquinavir
sertraline
sibutamine
sildenafil
simvastatin
sirolimus
sufentanil
tacrolimus
tamoxifen
testosterone
tolterodine
toremifene
triazolam
troleandomycin
verapamil
vinblastine
vincristine
R-warfarin
zaleplon
zileuton
zolpidem
zonisamide

CYP2C9

amiodarone
cimetidine
cortrimoxazole
fluconazole
***fluvoxamine
isoniazid
ketoconazole
metronidazole
zafirlukast

barbiturates
carbamazepine
rifampin
rifapentine
St. John's wort

carvedilol
celecoxib
diclofenac
flurbiprofen
fluvastatin
glimepiride
ibuprofen
irbesartan
losartan

montelukast
naproxen
phenytoin
piroxicam
tolbutamide
torsemide
S-warfarin
zafirlukast

CYP2C19

felbamate
fluoxetine
fluvoxamine
modafinil
omeprazole
oxcarbazepine

None

amitriptyline
citalopram
clomipramine
diazepam
imipramine

lansoprazole
phenytoin
omeprazole
R-warfarin

CYP2D6

amiodarone
chloroquine
cimetidine
clomipramine
diphenhydramine
fluoxetine
fluphenazine
haloperidol
paroxetine
perphenazine
propafenone
propoxyphene
quinacrine
quinidine
ritonavir
sertaline
terbinafine
thioridazine

None

amitriptyline
carvedilol
chlorpromazine
clomipramine
clozapine
codeine
desipramine
dextromethorphan
dihydrocodeine
donepezil
flecainide
fluoxetine
haloperidol
hydrocodone
imipramine
loratadine
maprotiline
methamphetamine

metoprolol
mexiletine
mirtazpine
nortriptyline
oxycodone
paroxetine
perphenazine
propafenone
propanolol
risperidone
ritonavir
thoridazine
timolo
tolterodine
tramadol
trazodone
venlafaxine