2016 Treatments for Acid-Peptic Diseases

Buffer acid
e.g. ALUMINUM HYDROXIDE, CALCIUM CARBONATE, MAGNESIUM HYDROXIDE, SODIUM BICARBONATE

Critical fact icon
Weak bases can be used to buffer stomach acid, and are used commonly as OTC medications. Antacids differ greatly in efficacy and side effects.

Mechanism of action

Al(OH)3 + 3HCl à AlCl3 + 3H2O
(Amphojel, ALternaGEL)

Mg(OH)2 + 2HCl  à MgCl2 + 2H2O
(combined with Al(OH)3:  Maalox, Mylanta, Gaviscon, Gelusil)

CaCO3 + 2HCl  à CaCl2 + H2O +CO2
(Tums)

NaHCO3 + HCl  à NaCl + H2O + CO2
(Alka Seltzer)

Email: Dr. Janet Fitzakerley | ©2016 University of Minnesota Medical School Duluth Campus | Last modified: 7-jan-16 8:27 PM