2015 Therapeutic Proteins

Advantages of antibody therapy

>65 antibodies are now approved for use, and ~350 are in clinical trials

 

  1. SPECIFICITY (“magic bullet”)
    increased therapeutic index

  2. NUMBER OF POTENTIAL TARGETS
    every epitope = potential therapeutic drug

  3. Long-term benefit to short-term therapy

  4. Diagnostic reagents - can test to see whether cells will respond before administering the drug

  5. Definition of disease process - e.g., identify cancer metastases using radiolabels

Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 27-apr-15 1:20 PM