This tests objectives 1 (naming of antibodies), 2 (differences between humanized and chimeric antibodies) and 3 (side effects of antibody treatment).

RituXImab is a chimeric antibody, which is more likely to cause a HAMA response (in its most severe form, this results in kidney damage) than a humanized antibody, like trastuZUmab;  therefore B is the correct answer.

Fever, anaphylaxis and headache are likely side effects of all antibodies (A is incorrect).  Chills, fever, arthralgia, diarrhea, vomiting, hypotension and respiratory distress are characteristics of cytokine release syndrome, which is a side effect of antibody treatment (C is incorrect).  Antibodies can cause the reactivation of TB (E is incorrect).  Causing cancer is not a generic problem with antibody treatment (rituximab is used to treat CD20-positive Hodgkin’s lymphoma; it doesn’t cause it), therefore D is incorrect.