2015 Folate, Vitamin B12 and Inhibitors

TRIMETHOPRIM

TRIMETHOPRIM (a folic acid inhibitor) is typically combined with SULFAMETHOXAZOLE (which blocks dihydropteroate synthetase).  These drugs act synergistically, blocking successive steps in the folate synthesis pathway in bacteria.

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Email: Dr. Janet Fitzakerley | ©2015 University of Minnesota Medical School Duluth | Last modified: 4-may-15 9:28 PM