Hearing / Endocochlear potential / Stria vascularis
Stria vascularis
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t
he stria vascularis, found on the lateral wall of the cochlea, produces the endolymph and is responsible for the endocochlear potential
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many of the ion transporters of the stria are the same as those in the kidney, so drugs that affect renal function are often ototoxic
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loop diuretics such as furosemide which blocks the Na+/K+/2Cl- transporter will decrease the EP, and raise acoustic thresholds