2016 Lower GI Pharmacology

Non-specific treatments of IBS

Non-specific treatments are the standard of care for irritable bowel syndrome (laxatives and cathartics for constipation-predominant IBS; opiates for diarrhea-predominant IBS). Specific agents targeting serotonin receptors have been developed as IBS treatments:  ALOSETRON, a 5HT3 antagonist that can be used in diarrhea-predominant IBS, and TEGASEROD, a 5HT4 agonist that is of benefit in constipation-predominant IBS. Both drugs have restricted availability. Critical facts icon
Email: Dr. Janet Fitzakerley | ©2016 University of Minnesota Medical School Duluth | Last modified: 25-jan-16 12:25 PM