2016 Lower GI Pharmacology

Osmotic (saline) cathartics
LACTULOSE, MAGNESIUM HYDROXIDE, SODIUM PHOSPHATE
POLYETHYLENE GLYCOL ELECTROLYTE SOLUTION

Mechanism of action

Therapeutic uses

Side effects

If absorbed systemically (e.g., SODIUM PHOSPHATE), all osmotic laxatives can cause intravascular volume depletion and electrolyte imbalances: hyperphosphatermia, hypocalcemia, hypernatremia, and hypokalemia. Although these drugs are very safe in most patients, they should be used with caution in patients who are frail, elderly, have renal insufficiency or have significant cardiac disease.

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Email: Dr. Janet Fitzakerley | ©2016 University of Minnesota Medical School Duluth | Last modified: 25-jan-16 12:25 PM