2012 Drugs that promote or inhibit coagulation

Activators of Antithrombin III: HEPARIN,
FONDAPARINUX,
LMW HEPARINS: DALTEPARIN, DANAPAROID, ENOXAPARIN

Mechanism

  1. Critical fact iconBind to antithrombin III, a protease inhibitor that complexes with ACTIVATED clotting factors IIa, IXa, Xa, XIa, XIIa and XIIIa (intrinsic system)
  1. HEPARIN also coats blood vessel wall (prevents platelet binding or causes permeabilization?)
Email: Dr. Janet Fitzakerley | ©2012 University of Minnesota Medical School Duluth | Last modified: 31-may-12 8:30 PM