2012 Drugs that promote or inhibit coagulation

Inhibitor of zymogen synthesis: WARFARIN

“Classic” cytochrome P450 interactions

Drugs that ALWAYS Interact with WARFARIN

Drugs that are LIKELY to be co-administered with WARFARIN
(due to co-morbidity, high prescription rate and/or OTC status)

  • thrombolytics, anticoagulants, and antiplatelet drugs
  • NSAIDS
  • anti-arrhythmics
  • antihyperlipidemics
  • uricosurics (anti-gout)
  • diuretics
  • analgesics and sedative hypnotics
  • antibiotics/antifungals (esp. cephalosporins)
  • GI drugs (esp. antacids)
  • thyroid medications
  • herbal supplements
Email: Dr. Janet Fitzakerley | ©2012 University of Minnesota Medical School Duluth | Last modified: 31-may-12 7:25 PM