2012 Drugs that promote or inhibit coagulation

Answer to example question 5

This tests: the differences between heparin and warfarin.

Heparin is given IV; warfarin is oral.  Heparin’s effects are immediate; warfarin has a delayed hypothrombic response (~ 1 week).  A major side effect of heparin is a transient thrombocytopenia (HIT).  Heparin is the effective in vitro anticoagulant.  Warfarin can cause chondrodysplasia punctata and hemorrhagic disorders in infants born to mothers taking the drug during the first trimester of pregnancy.  The answer is E.

Email: Dr. Janet Fitzakerley | ©2012 University of Minnesota Medical School Duluth | Last modified: 31-may-12 7:25 PM