2007 Sensory Physiology

Comparison of transduction in the special senses

 

AUDITION
(IHCs)

VISION
(rods)

OLFACTION
(ORNs)

Energy

Mechanical

Electromagnetic

Chemical

Type of receptor

Receptor
primary afferent

Receptor
primary afferent

Receptor =
primary afferent

Membrane receptor

Stretch

7TD family
Rhodopsin

7TD family
1000 types

G-protein

-----

Transducin

Golf

Effector protein

-----

Phosphodiesterase
(cGMP)

Adenylate cyclase
(cAMP)

Membrane channel

Non-specific cation
(inward
K+)

Non-specific cation
(inward
Na+)

Non-specific cation
(inward
Ca2+)

Channel response

Open

Close

Open

Membrane potential

Depolarize

Hyperpolarize

Depolarize

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