Somatosensation / Transmission / Pathways
Somatosensory pathways
- there are two primary somatosensory pathways (S&G Figure 10.15):
1st order neurons |
Output pathway |
2nd order neurons |
Output |
3rd order neurons THALAMUS |
Output pathway |
4th order neurons CORTEX |
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DORSAL COLUMN-MEDIAL LEMNISCUS (mechano- and proprioception)
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BODY | Dorsal root ganglia (DRG) |
Dorsal root/dorsal columns |
Dorsal column nuclei (medulla) |
Medial lemniscus (decussates in medulla) |
Ventroposterolateral nucleus (VPL) |
Internal capsule |
Postcentral gyrus (somatosensory cortex) |
HEAD | Cranial nerves V, VII, IX, X |
various |
Main trigeminal nucleus |
Trigeminal lemniscus (decussates in medulla) |
Ventroposteromedial nucleus (VPM) |
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SPINOTHALAMIC TRACT (thermoreception and nociception)
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BODY | Dorsal root ganglia (DRG) |
Lissauer's tract |
Dorsal horn nuclei (spinal cord) |
Spinothalamic tract (found in the anterolateral quadrant of the spinal cord) |
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Internal capsule |
Many, including:
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HEAD | Cranial nerves V, VII, IX, X |
Spinal trigeminal tract |
Spinal trigeminal nucleus |
- from a physiology perspective, there are three key points:
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the inputs from the body and head that form the medial and trigeminal lemnisci coalesce in the thalamus to form a single body map, which projects to the somatosensory cortex to form the humunculus
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both pathways are crossed (although they cross at different anatomical levels) - this means that somatosensory stimuli from one side are perceived in the contralateral cortex
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the spinothalamic tract projects to more diffuse areas of cortex, directly activating non-sensory regions
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